| Peach Bottom (2) | PA | York | Operational | 1.49 GW | Nuclear | Constellation Nuclear |
| Grand Gulf (1) | MS | Claiborne | Operational | 1.44 GW | Nuclear | System Energy Resources, Inc |
| Palo Verde (1) | AZ | Maricopa | Operational | 1.4 GW | Nuclear | Arizona Public Service Co |
| Palo Verde (2) | AZ | Maricopa | Operational | 1.4 GW | Nuclear | Arizona Public Service Co |
| Palo Verde (3) | AZ | Maricopa | Operational | 1.4 GW | Nuclear | Arizona Public Service Co |
| Peach Bottom (3) | PA | York | Operational | 1.37 GW | Nuclear | Constellation Nuclear |
| South Texas Project (1) | TX | Matagorda | Operational | 1.35 GW | Nuclear | STP Nuclear Operating Co |
| South Texas Project (2) | TX | Matagorda | Operational | 1.35 GW | Nuclear | STP Nuclear Operating Co |
| Millstone (3) | CT | New London | Operational | 1.35 GW | Nuclear | Dominion Energy Nuclear Conn Inc |
| Perry (1) | OH | Lake | Operational | 1.31 GW | Nuclear | Energy Harbor Nuclear Generation LLC |
| Wolf Creek Generating Station (1) | KS | Coffey | Operational | 1.29 GW | Nuclear | Wolf Creek Nuclear Optg Corp |
| Browns Ferry (3) | AL | Limestone | Operational | 1.29 GW | Nuclear | Tennessee Valley Authority |
| PSEG Hope Creek Generating Station (1) | NJ | Salem | Operational | 1.29 GW | Nuclear | PSEG Nuclear LLC |
| Browns Ferry (1) | AL | Limestone | Operational | 1.28 GW | Nuclear | Tennessee Valley Authority |
| Browns Ferry (2) | AL | Limestone | Operational | 1.28 GW | Nuclear | Tennessee Valley Authority |
| Watts Bar Nuclear Plant (1) | TN | Rhea | Operational | 1.26 GW | Nuclear | Tennessee Valley Authority |
| Watts Bar Nuclear Plant (2) | TN | Rhea | Operational | 1.26 GW | Nuclear | Tennessee Valley Authority |
| TalenEnergy Susquehanna (1) | PA | Luzerne | Operational | 1.26 GW | Nuclear | TalenEnergy Susquehanna LLC |
| TalenEnergy Susquehanna (2) | PA | Luzerne | Operational | 1.26 GW | Nuclear | TalenEnergy Susquehanna LLC |
| Nine Mile Point Nuclear Station (2) | NY | Oswego | Operational | 1.25 GW | Nuclear | Constellation Nuclear |
| Seabrook (1) | NH | Rockingham | Operational | 1.24 GW | Nuclear | NextEra Energy Seabrook LLC |
| Callaway (1) | MO | Callaway | Operational | 1.23 GW | Nuclear | Union Electric Co - (MO) |
| Braidwood Generation Station (1) | IL | Will | Operational | 1.22 GW | Nuclear | Constellation Nuclear |
| Braidwood Generation Station (2) | IL | Will | Operational | 1.22 GW | Nuclear | Constellation Nuclear |
| Byron Generating Station (1) | IL | Ogle | Operational | 1.22 GW | Nuclear | Constellation Nuclear |
| Byron Generating Station (2) | IL | Ogle | Operational | 1.22 GW | Nuclear | Constellation Nuclear |
| Sequoyah (1) | TN | Hamilton | Operational | 1.22 GW | Nuclear | Tennessee Valley Authority |
| Sequoyah (2) | TN | Hamilton | Operational | 1.22 GW | Nuclear | Tennessee Valley Authority |
| McGuire (1) | NC | Mecklenburg | Operational | 1.22 GW | Nuclear | Duke Energy Carolinas, LLC |
| McGuire (2) | NC | Mecklenburg | Operational | 1.22 GW | Nuclear | Duke Energy Carolinas, LLC |
| Fermi (2) | MI | Monroe | Operational | 1.21 GW | Nuclear | DTE Electric Company |
| Comanche Peak (1) | TX | Somervell | Operational | 1.21 GW | Nuclear | Luminant Generation Company LLC |
| Comanche Peak (2) | TX | Somervell | Operational | 1.21 GW | Nuclear | Luminant Generation Company LLC |
| Vogtle (1) | GA | Burke | Operational | 1.21 GW | Nuclear | Georgia Power Co |
| Vogtle (2) | GA | Burke | Operational | 1.21 GW | Nuclear | Georgia Power Co |
| Catawba (1) | SC | York | Operational | 1.2 GW | Nuclear | Duke Energy Carolinas, LLC |
| Catawba (2) | SC | York | Operational | 1.2 GW | Nuclear | Duke Energy Carolinas, LLC |
| Columbia Generating Station (2) | WA | Benton | Operational | 1.2 GW | Nuclear | Energy Northwest- Columbia |
| Waterford 3 (3) | LA | St Charles | Operational | 1.19 GW | Nuclear | Entergy Louisiana LLC |
| PSEG Salem Generating Station (1) | NJ | Salem | Operational | 1.17 GW | Nuclear | PSEG Nuclear LLC |
| PSEG Salem Generating Station (2) | NJ | Salem | Operational | 1.17 GW | Nuclear | PSEG Nuclear LLC |
| LaSalle Generating Station (1) | IL | LaSalle | Operational | 1.17 GW | Nuclear | Constellation Nuclear |
| LaSalle Generating Station (2) | IL | LaSalle | Operational | 1.17 GW | Nuclear | Constellation Nuclear |
| Diablo Canyon (2) | CA | San Luis Obispo | Operational | 1.16 GW | Nuclear | Pacific Gas & Electric Co. |
| Diablo Canyon (1) | CA | San Luis Obispo | Operational | 1.15 GW | Nuclear | Pacific Gas & Electric Co. |
| Donald C Cook (1) | MI | Berrien | Operational | 1.15 GW | Nuclear | Indiana Michigan Power Co |
| Limerick (1) | PA | Montgomery | Operational | 1.13 GW | Nuclear | Constellation Nuclear |
| Limerick (2) | PA | Montgomery | Operational | 1.13 GW | Nuclear | Constellation Nuclear |
| Clinton Power Station (1) | IL | DeWitt | Operational | 1.13 GW | Nuclear | Constellation Nuclear |
| Donald C Cook (2) | MI | Berrien | Operational | 1.13 GW | Nuclear | Indiana Michigan Power Co |
| Vogtle (3) | GA | Burke | Operational | 1.11 GW | Nuclear | Georgia Power Co |
| Vogtle (4) | GA | Burke | Operational | 1.11 GW | Nuclear | Georgia Power Co |
| St Lucie (1) | FL | St Lucie | Operational | 1.08 GW | Nuclear | Florida Power & Light Co |
| St Lucie (2) | FL | St Lucie | Operational | 1.08 GW | Nuclear | Florida Power & Light Co |
| River Bend (1) | LA | West Feliciana | Operational | 1.03 GW | Nuclear | Entergy Louisiana LLC |
| V C Summer (1) | SC | Fairfield | Operational | 1.02 GW | Nuclear | Dominion Energy South Carolina, Inc |
| Dresden Generating Station (2) | IL | Grundy | Operational | 1 GW | Nuclear | Constellation Nuclear |
| Dresden Generating Station (3) | IL | Grundy | Operational | 1 GW | Nuclear | Constellation Nuclear |
| Quad Cities Generating Station (1) | IL | Rock Island | Operational | 1 GW | Nuclear | Constellation Nuclear |
| Quad Cities Generating Station (2) | IL | Rock Island | Operational | 1 GW | Nuclear | Constellation Nuclear |
| Brunswick Nuclear (1) | NC | Brunswick | Operational | 1 GW | Nuclear | Duke Energy Progress - (NC) |
| Brunswick Nuclear (2) | NC | Brunswick | Operational | 1 GW | Nuclear | Duke Energy Progress - (NC) |
| Crane Clean Energy Center (1) | PA | Dauphin | Operational | 980.8 MW | Nuclear | Constellation Nuclear |
| North Anna (1) | VA | Louisa | Operational | 979.7 MW | Nuclear | Virginia Electric & Power Co |
| North Anna (2) | VA | Louisa | Operational | 979.7 MW | Nuclear | Virginia Electric & Power Co |
| Harris (NC) (1) | NC | Wake | Operational | 950.9 MW | Nuclear | Duke Energy Progress - (NC) |
| Arkansas Nuclear One (2) | AR | Pope | Operational | 942.5 MW | Nuclear | Entergy Arkansas LLC |
| Calvert Cliffs Nuclear Power Plant (2) | MD | Calvert | Operational | 932.4 MW | Nuclear | Constellation Nuclear |
| Davis Besse (1) | OH | Ottawa | Operational | 925.2 MW | Nuclear | Energy Harbor Nuclear Generation LLC |
| Edwin I Hatch (1) | GA | Appling | Operational | 924 MW | Nuclear | Georgia Power Co |
| Edwin I Hatch (2) | GA | Appling | Operational | 924 MW | Nuclear | Georgia Power Co |
| Beaver Valley (1) | PA | Beaver | Operational | 923.4 MW | Nuclear | Energy Harbor Nuclear Generation LLC |
| Beaver Valley (2) | PA | Beaver | Operational | 923.4 MW | Nuclear | Energy Harbor Nuclear Generation LLC |
| Calvert Cliffs Nuclear Power Plant (1) | MD | Calvert | Operational | 918 MW | Nuclear | Constellation Nuclear |
| Millstone (2) | CT | New London | Operational | 909.9 MW | Nuclear | Dominion Energy Nuclear Conn Inc |
| Arkansas Nuclear One (1) | AR | Pope | Operational | 902.5 MW | Nuclear | Entergy Arkansas LLC |
| Oconee (3) | SC | Oconee | Operational | 893.3 MW | Nuclear | Duke Energy Carolinas, LLC |
| Joseph M Farley (1) | AL | Houston | Operational | 888.2 MW | Nuclear | Alabama Power Co |
| Joseph M Farley (2) | AL | Houston | Operational | 888.2 MW | Nuclear | Alabama Power Co |
| Oconee (1) | SC | Oconee | Operational | 886.7 MW | Nuclear | Duke Energy Carolinas, LLC |
| Oconee (2) | SC | Oconee | Operational | 886.7 MW | Nuclear | Duke Energy Carolinas, LLC |
| James A Fitzpatrick (1) | NY | Oswego | Operational | 883.3 MW | Nuclear | Constellation Nuclear |
| Turkey Point (3) | FL | Miami Dade | Operational | 877.2 MW | Nuclear | Florida Power & Light Co |
| Surry (1) | VA | Surry | Operational | 847.5 MW | Nuclear | Virginia Electric & Power Co |
| Surry (2) | VA | Surry | Operational | 847.5 MW | Nuclear | Virginia Electric & Power Co |
| Palisades (1) | MI | Van Buren | Operational | 811.8 MW | Nuclear | Holtec Palisades, LLC |
| Cooper Nuclear Station (1) | NE | Nemaha | Operational | 801 MW | Nuclear | Nebraska Public Power District |
| H B Robinson (2) | SC | Darlington | Operational | 768.6 MW | Nuclear | Duke Energy Progress - (NC) |
| Turkey Point (4) | FL | Miami Dade | Operational | 760 MW | Nuclear | Florida Power & Light Co |
| Monticello Nuclear Facility (1) | MN | Wright | Operational | 685 MW | Nuclear | Northern States Power Co - Minnesota |
| Point Beach Nuclear Plant (1) | WI | Manitowoc | Operational | 643 MW | Nuclear | NextEra Energy Point Beach LLC |
| Point Beach Nuclear Plant (2) | WI | Manitowoc | Operational | 643 MW | Nuclear | NextEra Energy Point Beach LLC |
| Nine Mile Point Nuclear Station (1) | NY | Oswego | Operational | 641.8 MW | Nuclear | Constellation Nuclear |
| R E Ginna Nuclear Power Plant (1) | NY | Wayne | Operational | 614 MW | Nuclear | Constellation Nuclear |
| Prairie Island (1) | MN | Goodhue | Operational | 593.1 MW | Nuclear | Northern States Power Co - Minnesota |
| Prairie Island (2) | MN | Goodhue | Operational | 593.1 MW | Nuclear | Northern States Power Co - Minnesota |
| Kemmerer Unit 1 (KU1) | WY | Lincoln | Planned | 500 MW | Nuclear | US SFR Owner LLC |